Get predictions, betting odds and how to watch information for college football's Week 4 matchups with Top 25 teams.

The San Francisco 49ers will face the New Orleans Saints in Week 2 of the NFL season on Sunday at the Caesars Superdome.

The Pittsburgh Steelers seek a 2-0 start on Sunday with an early afternoon kickoff against Sam Darnold and the Seattle Seahawks. The game is scheduled to start at 1 p.m.