New research shows that the extracellular matrix protein LAMB1 accelerates esophageal squamous cell carcinoma by activating ...

Researchers from Capital Medical University, Beijing, China, have identified a CaN/NFATC3/Id3/E2A/Bmp4 signaling pathway that ...

A new Drosophila cancer atlas called ART-D maps ten genetically defined Ras-driven tumor models through three stages of ...

An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways involved in programmed cell death. The team identified the protein HERC4 as ...

Cells rely on complex signaling networks in which different molecular pathways communicate with one another. Small GTPases act as molecular switches in these networks, controlling diverse cellular ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

New research from the University of St Andrews has discovered a crucial piece in the puzzle of how all animals with a spine—including all mammals, fish, reptiles and amphibians—evolved. In a paper ...

Explore how oncogenes and signaling pathways converge and diverge in cancer, shaping diagnostic and therapeutic strategies for personalized interventions. This convergence is accompanied by ...

Vascular smooth muscle cells (VSMCs) line the medial layer of blood vessels and govern vascular tone, blood pressure and structural remodelling. Their capacity to contract, proliferate and secrete ...

Cytokinins are a class of phytohormones that orchestrate plant growth, development and adaptive responses to environmental challenges through a multistep phosphorelay system. Perceived by ...

Epithelial cells form the body's frontline barriers, helping keep microbes, toxins and other harmful substances out. Yet these protective cells are constantly exposed to threats, including microbial ...

Signaling networks are composed of numerous signaling pathways and each has its own intricate component parts. Signaling outputs are dynamic, extraordinarily complex and yet highly specific. In ...