DelveInsight's 'Sodium Channel Blockers Pipeline Insight 2025' report provides comprehensive global coverage of pipeline sodium channel blockers in various stages of clinical development, major ...

Nat Clin Pract Neurol. 2008;4(3):159-169. Drug Primary clinical use Protective effect during administration in animal models? Effects of withdrawal in EAE Clinical study Phenytoin Treatment of ...

The transport of ions to and from a cell is controlled by pore-forming proteins embedded in the cell membrane. In particular, voltage-gated sodium channels (VGSCs) govern the transfer of sodium (Na +) ...

A new review in the Journal of Neurology charts the rapid evolution of treatments for myotonic disorders, from established ...

A new study adds to evidence which suggests treating breast cancer patients with sodium channel blockers could be a promising future treatment to prevent the spread of cancer during the gap between ...

Dublin, Oct. 22, 2025 (GLOBE NEWSWIRE) -- The "Sodium Channel Blockers - Pipeline Insight, 2025" has been added to ResearchAndMarkets.com's offering. The "Sodium Channel Blockers - Pipeline Insight, ...

Atomic-level studies of the architecture of tiny sodium channel proteins, critical to generating electrical signals that start off each beat of the heart, are imparting striking details about their ...

The voltage-gated sodium channel α-subunit genes comprise a highly conserved gene family. Mutations of three of these genes, SCN1A, SCN2A and SCN8A, are responsible for a significant burden of ...

Thomas Kleyman, MD, professor of medicine and chief of the renal-electrolyte division at the University of Pittsburgh Medical Center, is a senior author of the study. Sodium channels found outside the ...

Discover the latest articles and news in related subjects. Amidation of the C-terminal carboxylic group of QYNAD completely abolished its activity, whereas acylation of the N-terminal amino group ...

Neurobiologist John Wood has long been interested in how animals feel pain. His research at University College London (UCL) typically involved knocking out various ion channels important in sensory ...

A study on live tissue cells is the first to reveal how channels that allow sodium to enter into breast cancer cells enable tumors to grow and spread. The discovery adds to evidence which suggests ...