A lineage-tracing study in mice shows that oocytes activated early in life can persist for nearly the entire reproductive ...

Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...

Learn more about the first-ever 3D map of an ovary and how it could reshape our understanding of fertility, menopause, and women's reproductive health. Researchers have developed a 3D map of an ovary ...

Oocytes are among the longest-lived cells. Scientists have been trying to understand what enables such longevity, because oocytes—like other nondividing, long-lasting cells—have a high risk of ...

How do immature egg cells maintain genetic quality for decades before they mature? Scientists find unusual safeguards in this quiescent cell that may inform research into fertility. Out of all the ...