A new narrative review maps the complex, context-dependent crosstalk between neurotransmitter systems and the NLRP3 ...

Inflammasome complexes are pivotal in the innate immune response. The NLR family pyrin domain containing protein 3 (NLRP3) inflammasome is activated in response to a broad variety of cellular ...

A new review argues that inflammasome-derived molecular biomarkers could predict wound outcomes, distinguish healing from ...

A team of researchers, affiliated with UNIST have unraveled the molecular mechanisms behind the activation of multiple inflammasomes and their role in inducing inflammatory cell death. This discovery ...

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is ...

Neuronal inflammation is the common denominator in diseases such as Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, Age-Related Macular Degeneration and Type 2 Diabetes, that have ...

SARS-CoV-2, which belongs to the family Coronaviridae, is a highly infectious virus that mainly infects the respiratory tract of humans. The viral genome of SARS-CoV-2 is found within the nucleocapsid ...

Liangbo Linus Shen, MD, shared phase 2 data showing kamuvudine K8 reduced geographic atrophy growth by 54%.

An experimental drug called kamuvudine-9 helped reverse pre-existing vision loss and paralysis in animal models of multiple sclerosis, according to a<a class="excerpt-read-more" href=" More ...

Medical scientists have demonstrated that important pro-inflammatory mediators are released into the bloodstream through tiny pores in the cell membrane at a very early stage of the immune response.

There are various studies that have explored the role of the body’s circadian rhythm in regulating immune activity. Disruptions in the circadian rhythms exacerbate inflammation. Researchers from the ...